Wenjing Zhao

Affiliated Hospital, Hebei University of Engineering, Neural family, Handan, 056000, China;

Abstract: Objective: To investigate the relationship between carotid atherosclerotic plaques and resistin, in-terleukin 6 (il-6), and interleukin 1 (il-1) in elderly patients with acute progressive cerebral infarction. Meth-ods：It was selected that 113 elderly patients with acute progressive cerebral infarction who were hospital-ized from June 2016 to December 2018.First of all, the patients were divided into the non-plaque group (n = 30) and the plaque group (n = 83) according to the carotid artery ultrasound results, then according to the characteristics of plaques, the patients were further divided into stable plaques group (n = 32) and unstable plaques group (n = 51), Serum resistin, IL-6, and IL-1βwere compared between the each groups. Result: it was higher than in the non-plaque group that the levels of resistin, IL-6 and IL-1β in the plaque group, and it was statistically significant of the differences between the two groups P <0.05); (2) it was significantly higher that the levels of resistin, IL-6 and IL-1β in the unstable plaque group than that in the stable plaque group (P <0.05), and it was statistically significant of the differences between the two groups P <0.05). Conclusion: It is associated with that carotid artery plaque instability and the progression of cerebral infarction in elderly pa-tients, And It closely related to that carotid plaque instability and the levels of resistance, IL-6 and IL-1β.

Keywords: Resistance; IL-6; IL-1β; Progressive cerebral infarction; Carotid; Atherosclerotic plaques