Observation of the Therapeutic Effect of Mongolian Medicine Sedeng-4 Nanoemulsion on 112 Cases of Pruritus Dermatosis

Wurina1,3, Bold Sharav2, Enkhtur Yadamsuren1, Rina Du4*

1International School of Mongolian Medicine, Mongolian National University of Medical Sciences, Uulaanbaatar, 999097-15141, Mongolia

2Department of Dermatology School of Medicine, Mongolian National University of Medical Sciences, Uulaanbaatar, 999097-15141, Mongolia

3Inner Mongolia Medical University, Huhhot, 010010, China

4Inner Mongolia International Mongolian Hospital, Huhhot, 010010, China

Abstract: This electronic document is a “live” template. The various components of your paper [title, text, heads, etc.] are already defined on the style sheet, as illustrated by the portions given in this document. (Abstract) Purpose: To explore the treatment efficacy of Mongolian medicine Sedeng-4 Nanoemulsion on 112 Cases of Pruritus Dermatosis. Methods: 112 patients with pruritus dermatosis in dermatology were selected from May 2018 to June 2019. They are randomly divided into observation group and Dycloninae Hydrochloric Cream control group, Doxepine Hydrochloride Cream control group, of which 38 cases were observed, 37 cases were controlled against Dycloninae Hydrochloric Cream, 37 cases were in the control of Doxepine Hydrochloride cream. The effect of clinical treatment and the occurrence of adverse reactions were compared. Results: After 2 weeks of treatment, the symptoms of patients improved, and the differences between the three groups were not statistically significant (P>0.05); and the indicators of the observation group were significantly better than those of the other two control groups in the 4th to 8th week, with a total efficiency rate higher than that of the Dycloninae Hydrochloric Cream control group and the Doxepine Hydrochloride Cream control group. The differences in the three groups were statistically significant (P<0.05); the adverse reaction rates in the observation group were lower than those of the control group of Dycloninae Hydrochloric Cream and the control group of Doxepine Hydrochloride Cream (P<0.05). Conclusion: The clinical efficacy of Mongolian Medicine Sedeng-4 Nanoemulsion on 112 Cases of Pruritus Dermatosis is significant. With higher safety level and fewer cases of adverse reactions, it is worth popularizing in clinical practice.

Keywords: Mongolian medicine sedeng-4 nanoemulsion; Patients with pruritus dermatosis; Clinical efficacy; Adverse reaction